Yash,
Where did these powders come from, ore, or from other metals, what made them into copper sulfate, gold and silver?
Copper sulfate is water soluble in boiling water (as long as it is not copper sulfide from ore), also the materials would need incineration before processing further.
Are the powders dry? What color are they, the more details you give, the better advice you could get.
We need more detail of where this powder came from; also do you know percentages of metals involved.
Before we can recommend any step to take with these powders.