If you have a bead from an ore source and this bead has all the physical characteristics of being formed from gold metal, cuts, flattens and bends like lead but with a different colour, and the bead disappears when cupelled the most likely explanation is the presence of tellurium in the bead.
Tellurium is notorious for taking the gold into a cupel from a bead, it is mentioned in many books on fire assaying.
Gold Telluride minerals are common in many areas of the world with some areas such as Cripple Creek in Colorado being famous for the difficulty of getting full or even any gold values in fire assay.
Some tellurides will yield their gold in cyanide solution, others will not, it requires testing to see if your ore will react well to cyanide leaching.
Many telluride ores which will yield the gold when cyanide leached as run of mine ore will not leach the gold if the tellurides are concentrated by gravity or flotation before leaching.
Other metals will also cause problems when they are present as gold minerals but tellurium is the most common in ores.
Attached is an ASAT bulletin on gold minerals, ASAT no longer exists but the bulletin is the best reference source available.